NEWS. NFL Week 4 picks: Upset and score predictions, matchup breakdowns for every game. Who'll own first place in the AFC North after tonight's showdown between the Steelers and Browns? Will the Chiefs or Raiders take Sunday's rivalry bout between ...

Here's Sporting News' latest fearless forecast of professional pigskin prognostications for Week 4 of the 2026 NFL season.

The Kansas City Chiefs have had the Las Vegas Raiders' number throughout the Patrick Mahomes era, and Trevor Knapp expects that trend to continue in his latest NFL moneyline picks.

The SportsLine projection model, which entered Week 4 on a 54-43 run, reveals Indianapolis Colts vs. Washington Commanders picks for the NFL Week 4 game in London

Brock Purdy has been the MVP of the league through three weeks, and he has a big test this weekend against Denver’s defense. The Broncos have continued their trend of starting games slowly early on this year, and if that happens again against this 49ers offense, I just don’t see them finding their way back.

NFL projection model reveals its exact Week 3 NFL score predictions and picks for each game after 10,000 simulations

Get NFL Week 4 ATS picks for every game, with Chris Vasile’s against-the-spread predictions, matchup analysis, injuries, and betting edges.